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This glucose hypometabolism can potentially be countered by providing a dietary source of substrate to increase serum ketone bodies (23, 24) with, in the case of MCI, a direct and significant benefit in several cognitive domains (25)

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Finally, a 2007 review of the literature highlighted that plasma coenzyme Q 10 concentrations higher than normal were likely needed to promote coenzyme Q 10 uptake by peripheral tissues and different tissues may indeed require different plasma thresholds for the uptake of coenzyme Q 10 (102)

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Deng ZY, Zhang JW, Li J, Fan YW, Cao SW, Huang RL, Yin YL, Zhong HY, Li TJ (2007) Effect of polysaccharides of cassiae seeds on the intestinal microflora of piglets